Metagenics
UltraGI Replenish® is a specialized medical food engineered for the nutritional management of compromised gastrointestinal function and malabsorption. This advanced formula supports individuals with leaky gut or chronic digestive distress through a clinically balanced blend of macro and micronutrients designed to nourish the intestinal lining. Featuring a proprietary prebiotic blend and targeted amino acids like L-glutamine, it promotes gut barrier integrity and a healthy microbiome. The addition of easily digestible proteins and bioactive compounds further supports cellular repair and nutrient uptake for comprehensive digestive stability and intestinal health.
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UltraGI Replenish® is a scientifically advanced medical food formulated for the nutritional management of patients with compromised gastrointestinal function. Designed to address malabsorption and digestive distress, it features a clinically tested blend of nutrients intended to nourish the intestinal cells and support the delicate balance of the gut microbiome. By providing targeted prebiotic support and specialized amino acids, this formula helps maintain gut barrier integrity and supports the body’s natural repair processes for long-term intestinal stability.
The foundation of UltraGI Replenish is its sophisticated prebiotic profile, featuring 2g of 2’-Fucosyllactose (2’-FL). This unique prebiotic, historically found in human milk, specifically encourages the growth of beneficial bacteria. Combined with 5g of Isomalto-oligosaccharides, these nutrients work synergistically to optimize the intestinal environment, improve digestive comfort, and support a healthy and diverse microbiome.
To support the physical lining of the gastrointestinal tract and promote healthy gut barrier function, the formula includes 500mg of L-Alanyl-L-Glutamine. This highly stable dipeptide is more easily absorbed than standard glutamine, providing essential fuel for intestinal cells. The formula is further enhanced with a high-dose of L-Lysine (1,650mg) and added BCAAs, providing the building blocks necessary for maintaining lean tissue and supporting systemic recovery. Additionally, Flaxseed-derived ALA provides 400mg of Alpha-Linolenic Acid to support a healthy inflammatory response within the gut.
Recognizing that compromised gut health often leads to nutrient deficiencies, UltraGI Replenish includes a bioavailable nutrient suite featuring Methylcobalamin (B12) and Calcium L-5-methyltetrahydrofolate (L-5-MTHF). These methylated forms ensure that patients with absorption challenges or MTHFR variations receive superior cellular support. The formula also provides 100% DV of Zinc and 340% DV of Chromium to support vital enzymatic function and metabolic health during the repair process.
This formula utilizes a gentle blend of Pea and Rice protein isolates, delivering 12g of easily digestible plant-based protein that is easy on the digestive system. For energy, it is formulated with Olive Oil and Medium-Chain Triglycerides (MCTs), providing easily accessible fuel that does not stress the gallbladder or digestive tract. This strictly non-GMO and gluten-free formula is naturally sweetened with Monk Fruit to ensure a clean, professional-grade taste profile.
UltraGI Replenish features 2’-FL, a unique prebiotic that acts as a decoy for harmful bacteria while providing specific nourishment for beneficial Bifidobacteria. This helps strengthen the gut’s immune response and supports the recovery of the intestinal lining.
The L-Alanyl-L-Glutamine found in UltraGI Replenish is a more stable and soluble dipeptide form than standard glutamine. It is absorbed more efficiently by the gut wall, providing rapid cellular fuel to help repair the intestinal barrier and support those with “leaky gut” or malabsorption.
No, UltraGI Replenish is naturally sweetened with Monk Fruit (Luo Han Guo) and is strictly free from artificial sweeteners, sucralose, and aspartame. This ensures a clean formulation that avoids the common GI triggers associated with synthetic additives.
UltraGI Replenish addresses nutrient deficiencies common in malabsorption by providing a comprehensive suite of bioavailable vitamins and minerals. This includes methylated B12 and Folate, which are in their “active” forms to ensure maximum absorption even when gastrointestinal function is compromised.
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